Division of Nephrology, Department of Medicine

Tetrahydrocannabinol (THC), the primary psychoactive cannabinoid compound found in cannabis, binds to the cannabinoid receptor type 1 (CB1) in the brain producing the subjective “high” feeling, in addition to other effects throughout the brain. This image is at the intersection of two cerebellar lobes and the cerebral cortex of a mouse brain demonstrating the location of CB1 (brown).