Sam Fein deconstructs interpersonal relations and emotional conditions within social frameworks of power. She explores how social hierarchies form, how authority is determined and maintained, and how implicit messages of power are communicated.

The artworks draw upon personal history, mining her upbringing to fuse memory with imagination. The densely-layered narratives present a form of visual storytelling that is both comedic and bizarre. Bold colors, quirky characters, whimsical scenes, and symbolic details contrast a darker psychological underpinning, creating a disjointed and unsettling reality.

Embracing paradox, her art highlights the subjectivity of meaning-making within human experience and questions the notion of a single objective truth. Rather than replicating the literalism of the physical world, each piece gives voice to uniquely individualized reality.