Departments of Oncological Sciences and Neurosurgery

This image shows GFAP-positive reactive astrocytes (red) within mouse glioblastoma (GBM).

Astrocytes regulate water homeostasis in the brain via the water channel aquaporin 4 (AQP4).

Here we see AQP4 mRNA (yellow dots) concentrated within the cell body of astrocytes within the tumor core.